文章摘要
第五强强,李博艺,李颖,徐峰,刘成成,他得安.空间频率域超声背散射参量用于骨质状况的评价*[J].,2018,37(1):145-151
空间频率域超声背散射参量用于骨质状况的评价*
Spatial frequency domain ultrasonic backscatter parameters for evaluation of bone
投稿时间:2017-11-22  修订日期:2017-12-28
中文摘要:
      在超声背散射骨质评价中,不同测量感兴趣区域(ROI)的超声背散射信号会有波动,致使诊断准确度降低。本文目的是研究超声背散射信号随测量区域的变化规律。采用空间扫描方法离体测量了35块骨样本不同ROI的超声背散射信号,经过空间域傅里叶变换,将超声背散射参数从空间域变换到空间频率域。结果表明,在空间频率域,超声背散射参数的主要频率成分集中于低空间频率部分,说明超声背散射参数随着不同ROI的变化大致保持稳定,仅有少量波动;空间频率域超声背散射参量最大值(MASF)与骨矿密度等参数具有中高度显著相关性(R2=0.45-0.83,p<0.001);空间频率域超声背散射参量衰减系数(AC)也与松质骨密度及结构特征有显著相关性(R2=0.41-0.72,p<0.001)。研究表明空间频率域变换方法有助于明确超声背散射信号随测量ROI的变化规律,空间频率域的超声背散射相关新参量评价松质骨状况具有可行性。
英文摘要:
      Ultrasonic backscattering signals changed with the different regions of interest (ROI) in ultrasonic backscattering bone evaluation, resulting in the decrease of diagnostic accuracy. The purpose of this paper is to study the variation of ultrasonic backscatter signals with the ROI changes. 35 cancellous bone specimens were measured in vitro and ultrasonic backscatter signals of different ROI were obtained by spatial scanning measurement. Ultrasonic backscattering parameters were transformed from the spatial domain to the spatial frequency domain by spatial domain Fourier transform. The results show that in the spatial frequency domain, the main frequency components of ultrasonic backscattering parameters were concentrated in the low spatial frequencies, indicating that ultrasonic backscattering parameters remain roughly stable with only a few fluctuations with different ROI changes. The maximum amplitude of ultrasonic backscattering parameters in spatial frequency domain (MASF) had highly significant correlation with bone mineral density and other parameters (R2=0.45-0.83, p<0.001). The attenuation coefficients of ultrasonic backscattering parameters in spatial frequency domain (AC) were also significantly related to the cancellous bone density and structure features (R2=0.41-0.72, p<0.001). This article shows that the method of spatial frequency domain transformation is helpful for clarifying the variation of ultrasonic backscatter signals with the ROI changes. The new parameters obtained by ultrasonic backscattering in spatial frequency domain are feasible to evaluate cancellous bone.
DOI:10.11684/j.issn.1000-310X.2018.01.021
中文关键词: 松质骨,超声背散射,空间频率域
英文关键词: Cancellous bone, Ultrasonic backscattering, Spatial frequency domain
基金项目:国家自然科学基金项目 (11525416, 11504057, 11604054)
作者单位E-mail
第五强强 复旦大学电子工程系 16210720136@fudan.edu.cn 
李博艺 复旦大学电子工程系 16110720100@fudan.edu.cn 
李颖 复旦大学电子工程系 14110720073@fudan.edu.cn 
徐峰 复旦大学电子工程系 xf@fudan.edu.cn 
刘成成 同济大学声学研究所 chengchengliu@tongji.edu.cn 
他得安 复旦大学电子工程系 tda@fudan.edu.cn 
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