Page 82 - 《应用声学》2023年第6期

第 42 卷 第 6 期 Vol. 42, No. 6
2023 年 11 月 Journal of Applied Acoustics November, 2023

⋄ 研究报告 ⋄

高强度聚焦超声治疗子宫肌瘤中水囊耦合的

影响评估 ∗

陈燕华 1 冯 炼 1 周 芳 1 王永领 2 周小伟 1†

(1 超声医学工程国家重点实验室 重庆医科大学生物医学工程学院 重庆 400016)
(2 超声医疗国家工程研究中心 重庆 401121)
摘要：水囊作为一种特殊的辅助器件在高强度聚焦超声治疗子宫肌瘤的过程中发挥着重要作用，但它同时
也会让声通道变得更加复杂，对超声治疗效率和超声引导影像均造成负面影响。基于实际临床场景，利用
k-Wave 声学仿真软件建立高强度聚焦超声辐照靶组织及其超声引导过程的仿真模型，在有无水囊两个场景
下，对治疗效率和监控影像质量进行定量评估。结果表明，加入水囊后，声波的聚焦性变差，焦域处的最高温度
降低；通过分析超声图像的分辨率、对比度、对比噪声以及背景信噪比，发现加入水囊后超声图像的质量降低。
建立的数值仿真模型能够初步评估水囊对治疗效率和监控影像质量的影响，可作为一种评估体系用于优化水
囊参数，如水囊材料、厚度、形状、内部溶液成分等，为下一步实验探索对治疗效率和影像质量影响最小的水囊
耦合方式提供评估手段。
关键词：高强度聚焦超声；水囊；k-Wave；治疗效率；成像质量
中图法分类号: R318 文献标识码: A 文章编号: 1000-310X(2023)06-1192-08
DOI: 10.11684/j.issn.1000-310X.2023.06.011

Evaluation of the effect of water bag on high intensity focused ultrasound in the
treatment of uterine fibroids

CHEN Yanhua 1 FENG Lian 1 ZHOU Fang 1 WANG Yongling 2 ZHOU Xiaowei 1

(1 State Key Laboratory of Ultrasound in Medicine and Engineering, College of Biomedical Engineering, Chongqing Medical
University, Chongqing 400016, China)
(2 National Engineering Research Center of Ultrasound Medicine, Chongqing 401121, China)

Abstract: As a special coupling method, water bag plays an important role in the treatment of uterine
fibroids by high-intensity focused ultrasound. However, it also makes the acoustic passage more complicated
and negatively affects the efficiency of ultrasound treatment and the quality of ultrasound-guiding image.
Based on the realistic clinical settings, k-Wave acoustic simulation software was used to establish a model of
the target tissue being irradiated by high-intensity focused ultrasound and its ultrasonic guidance process. The
therapeutic efficiency and guiding image quality were quantitatively evaluated in two scenarios with or without
water bag. These results show that the acoustic focusing became worse and the maximum temperature at the
focal region decreased after the water bag was added. By analyzing the resolution, contrast, contrast noise and

2022-07-18 收稿; 2022-11-07 定稿
2021 年重庆市留学人员回国创业创新支持项目 (cx2021022)
∗
作者简介: 陈燕华 (1996– ), 女, 广西北海人, 硕士研究生, 研究方向: 超声影像监控。
† 通信作者 E-mail: zhou.xiaowei@cqmu.edu.cn