Page 135 - 201903

第 38 卷 第 3 期 张艳秋等： 剪切波对 HIFU 经颅聚焦形成温度场影响的数值仿真研究 417

x y
300
300

250
250

200
200
λ max
λ max
θ
θ
150 150
15 mm 98 mm 45 mm
28 mm
98 mm 45 mm
28 mm 7 mm
100 100
7 mm
50 50

0 50 100 150 200 z 0 50 100 150 200 z
(a) x-z䶒 (b) y-z䶒

图 7 超声最大入射角度计算示意图
Fig. 7 Schematic diagram of the maximum incident angle of ultrasound

[8] Clement G T, Sun J, Hynynen K. The role of internal
参 考 文 献 reflection in transskull phase distortion[J]. Ultrasonics,
2001, 39(2): 109–113.
[1] Zhao W P, Chen J Y, Chen W Z. Dynamic contrast- [9] Connor C W, Hynynen K. Patterns of thermal deposi-
enhanced MRI serves as a predictor of HIFU treat- tion in the skull during transcranial focused ultrasound
ment outcome for uterine fibroids with hyperintensity surgery[J]. Biomedical Engineering, IEEE Transactions
on, 2004, 51(10): 1693–1706.
in T2-weighted images[J]. Experimental & Therapeutic
Medicine, 2016, 11(1): 328–334. [10] White P J, Clement G T, Hynynen K. Longitudinal
[2] Gelet A, Crouzet S, Rouviere O, et al. High-intensity and shear mode ultrasound propagation in human skull
focused ultrasound (HIFU) for prostate cancer[J]. Can- bone[J]. Ultrasound in Medicine & Biology, 2006, 32(7):
cer Control Journal of the Moffitt Cancer Center, 2012, 1085–1096.
14(14): 244–249. [11] Pinton G, Aubry J F, Fink M, et al. Effects of nonlinear
[3] Deckers R, Merckel L G, Senneville B D D, et al. Per- ultrasound propagation on high intensity brain therapy[J].
formance analysis of a dedicated breast MR-HIFU system Medical Physics, 2011, 38(3): 1207–1216.
for tumor ablation in breast cancer patients[J]. Journal of [12] Jones R M, Hynynen K. Comparison of analytical and
Therapeutic Ultrasound, 2015, 3(1): 43. numerical approaches for CT-based aberration correction
[4] Li Y J, Huang G L, Sun X L, et al. The combination ther- in transcranial passive acoustic imaging[J]. Physics in
apy of high-intensity focused ultrasound with radiother- Medicine & Biology, 2016, 61(1): 23–26.
apy in locally advanced pancreatic carcinoma[J]. World [13] Ding X, Wang Y, Zhang Q, et al. Modulation of transcra-
Journal of Surgical Oncology, 2016, 14(1): 60. nial focusing thermal deposition in nonlinear HIFU brain
[5] Elias W J, Huss D, Voss T, et al. A pilot study of focused surgery by numerical simulation.[J]. Physics in Medicine
ultrasound thalamotomy for essential tremor[J]. New Eng- & Biology, 2015, 60(10): 3975.
land Journal of Medicine, 2013, 369(7): 640–648. [14] 王祥达, 苏畅, 林伟军, 等. 剪切波对时间反转调相的经颅聚
[6] Mcdannold N, Clement G, Black P, et al. Transcranial 焦超声的影响 [J]. 应用声学, 2018, 37(3): 315–323.
MRI-guided focused ultrasound surgery of brain tumors: Wang Xiangda, Su Chang, Lin Weijun, et al. Influence
initial findings in three patients[J]. Neurosurgery, 2010, of shear waves on transcranial focused ultrasound using
66(2): 323–332. time-reversal-based phase modulations[J]. Journal of Ap-
[7] King R L, Brown J R, Newsome W T, et al. Effective plied Acoustics, 2018, 37(3): 315–323.
parameters for ultrasound-induced in vivo, neurostimula- [15] Bailey M R, Khokhlova V A, Sapozhnikov O A, et
tion[J]. Ultrasound in Medicine & Biology, 2013, 39(2): al. Physical mechanisms of the therapeutic effect of ul-
312–331. trasound (a review)[J]. Acoustical Physics, 2003, 49(4):