Page 67 - 《应用声学》2022年第5期
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第 41 卷 第 5 期                                                                       Vol. 41, No. 5
             2022 年 9 月                          Journal of Applied Acoustics                 September, 2022

             ⋄ 研究报告 ⋄


                    基于声表面波-气相色谱联用技术快速分析


                                            麝香中的麝香酮                        ∗



                   陆艳艳      1  沈 刚     2   王剑波     2   朱宏伟     1   赵军宁      2†   郝俊杰     1   何世堂     1†



                                              (1  中国科学院声学研究所      北京   100190)
                                               (2  四川省中医药科学院      成都  610041)

                摘要：建立声表面波气相色谱仪现场快速检测麝香中主要成分麝香酮的方法。取麝香样品经过超声、过滤后，
                使用声表面波气相色谱仪进行检测。DB-5 毛细管色谱柱初始温度 45 C，以 10 C/s 程序升温至 180 C，检测
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                器温度 40 C。麝香酮在 7 s 内出峰，最低检测限为 15.8 pg，精密度相对标准偏差值为 2.10%∼3.84%，重复性相
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                对标准偏差值为 4.23%，稳定性相对标准偏差值为 4.49%，麝香酮溶液在 0.2 ∼ 10 µg/mL 质量浓度范围内线性
                良好。测试 16 组麝香样品，麝香酮含量在 2.08% ∼ 3.83% 范围内。麝香酮含量最高的为四川圭兴林麝，含量最
                低的为陕西凤县林麝。三年生的林麝和马麝中麝香酮含量均大于一年生的林麝和马麝。声表面波气相色谱仪
                检测麝香酮具有较好的响应特性、精密度、重复性和稳定性，建立的声表面波气相色谱方法能够实现麝香中主
                要成分麝香酮快速、准确的定量检测。
                关键词：麝香酮；声表面波；气相色谱；快速检测；定量分析
                中图法分类号: TP212.9           文献标识码: A         文章编号: 1000-310X(2022)05-0743-06
                DOI: 10.11684/j.issn.1000-310X.2022.05.008



               Rapid analysis of musk ketone in musk based on gas chromatography-surface
                                              acoustic wave technology



                       LU Yanyan  1  SHEN Gang  2  WANG Jianbo  2  ZHU Hongwei  1  ZHAO Junning  2
                                                HAO Junjie 1  HE Shitang 1


                               (1  Institute of Acoustics, Chinese Academy of Sciences, Beijing 100190, China)
                                (2  Sichuan Academy of Chinese Medicine Sciences, Chengdu 610041, China)
                 Abstract: A rapid detection method of musk ketone which the main component of musk has been developed
                 using gas chromatography with surface acoustic wave detector (GC-SAW). Musk samples were detected by
                 using GC-SAW after ultrasonic and filtration. The initial temperature of DB-5 capillary column was 45 C,
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                 and was temperature-programmed to 180 C with the rate of 10 C/s, the detector temperature was 40 C. The
                 retention time of muscone was in 7 s, the lowest detection quantity was 15.8 pg, the precision relative standard
                 deviation (RSD) value was 2.10%–3.84%, the repeatability RSD value was 4.23%, the stability RSD value was
                 4.49%. The linearity is good in the concentration range of 0.2–10 µg/mL. Test 16 groups of musk samples,
                 the content of muscone is between 2.08% and 3.83%. The highest content of musk ketone is the forest musk
                 deer in Guixing, Sichuan, and the lowest content is the forest musk deer in Fengxian, Shaanxi. The content of
             2021-07-12 收稿; 2021-11-29 定稿
             四川省财政专项 (ZJ-201903-0011)
             ∗
             作者简介: 陆艳艳 (1985– ), 女, 湖南人, 硕士, 副研究员, 研究方向: 药物分析研究。
             † 通信作者 E-mail: zarmy@189.cn; heshitang@mail.ioa.ac.cn
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